Calling amplified haplotypes in next generation tumor sequence data
نویسندگان
چکیده
منابع مشابه
Calling amplified haplotypes in next generation tumor sequence data.
During tumor initiation and progression, cancer cells acquire a selective advantage, allowing them to outcompete their normal counterparts. Identification of the genetic changes that underlie these tumor acquired traits can provide deeper insights into the biology of tumorigenesis. Regions of copy number alterations and germline DNA variants are some of the elements subject to selection during ...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2011
ISSN: 1088-9051
DOI: 10.1101/gr.122564.111